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Research areas

Scientific hypotheses

Research activities within CIRRO will test the following three hypotheses, which also categorize the research areas of the center:

  1. Clinical radiobiological factors important for individual tumour and normal tissue response can be identified.
  2. Functional biological imaging is able to detect relevant biological sub-volumes both before and during radiotherapy on an individual basis, and biological images can be correlated with patho-anatomical entities in 3D to derive at biological contours for planning of radiotherapy.
  3. Image guided adaptive intensity-modulated radiotherapy is able to deliver additional dose to resistant sub-volumes without surpassing dose volume constraints for normal tissue tolerance.